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The data and evidence used in the consultation stage impact assessments reflects the best available at the time of their completion in October 2025 (May 2026 for the partial BRIA for Scotland, and June 2026 for the impact assessments for Wales and Northern Ireland)

Adverse events occurred at similar rates of 2%7% in both intervention and control groups in 2 RCTs ( n = 999 and n = 300).28 , 39 In another study, both intervention and control groups had 80% 86% reporting at least 1 adverse event;27 n = 657

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